United looked more solid after the introduction of midfielder Nemanja Matic at the break and got a foothold in the tie through a 70th-minute goal from Marcus Rashford.
IMAGES from the English Premier League matches played on Saturday.
Spain goalkeeper Iker Casillas has given a strong indication that he will retire from international footbal after 16 years. The 35-year-old did not play in any of Spain's four games at Euro 2016 with national team coach Vicente del Bosque picking Manchester United's David De Gea in goal. Casillas, who made his debut in 2000 and is Spain's most capped player with 167 appearances, posted a video on his twitter account (@casillasworld) of a Rambo film with the dialogue saying: "I don't know where but I'm going."
The defeat halted Brighton's impressive three-game winning streak which included a 4-1 win over Chelsea and a 3-1 victory at Arsenal in the League Cup on Wednesday.
United looked dead and buried as they struggled to get back into the contest after the break but 19-year-old Brandon Williams's first senior goal 18 minutes from time sparked them into life. However, substitute McBurnie denied the visitors in stoppage time to add a further twist to the breathless encounter, squeezing a strike past De Gea, with the goal awarded after a lengthy VAR review.
Manchester United produced an utterly unexpected 2-1 victory over old rivals Liverpool in the Premier League at Old Trafford on Monday to turn fan protests against the club's owners into a rare night of celebration.
Five talking-points from the Premier League weekend after Manchester United extended their winning run against Tottenham Hotspur, Liverpool were made to work hard for their win at Brighton & Hove Albion and Arsenal losing at West Ham United.
Ronaldo answered his critics five minutes after halftime with a superb finish
Ronaldo's 62nd minute strike was his 17th league goal this season
Lionel Messi scored and grabbed two assists as La Liga leaders Barcelona eased to a 4-0 win away to struggling Real Mallorca on Saturday, making the perfect return to action after Spanish football's three-month hiatus due to the COVID-19 pandemic. The win takes Barca on to 61 points after 28 games, five clear of nearest challengers Real Madrid, who host Eibar on Sunday in their first game back.
World Cup winner Paul Pogba's third minute penalty and a late goal from Luke Shaw gave Manchester United a 2-1 win over Leicester City at Old Trafford in the opening game of the Premier League season on Friday.
IMAGES from EPL matches played on Thursday.
Liverpool defender Martin Skrtel was charged with violent conduct for appearing to stamp on Manchester United goalkeeper David De Gea.
Everton and Manchester United drew 1-1 at Goodison Park in the Premier League on Sunday in an enthralling game which ended with late VAR drama.
For all Vicente del Bosque's confidence that he has the right balance of experience and youth to return Spain to their familiar place on the winner's rostrum, questions remain about his best starting line-up ahead of Euro 2016.
Steven Bergwijn scored twice in stoppage time as Tottenham Hotspur stunned Leicester City and pulled off a remarkable 3-2 victory in the Premier League on Wednesday.
You may be entranced by the foot magic, but don't miss the hair cuts!
Erling Haaland and Phil Foden scored hat-tricks to fire champions Manchester City to a rampant 6-3 thrashing of local rivals Manchester United in the English Premier League on Sunday.
Rohan Bopanna catches up with Manchester United trio at Wimbledon.
Spain scored a stoppage-time equaliser through Jose Luis Gaya to draw 1-1 away to Germany on Thursday in their Nations League opener and first international in almost 10 months due to the COVID-19 pandemic.
Images from the Premier League matches played on Sunday.
A rejuvenated Manchester United claimed a sixth win from six matches since former striker Ole Gunnar Solskjaer stepped in following the sacking of Jose Mourinho.
Mason Greenwood's late winner earned Manchester United a 1-0 win at wasteful Wolverhampton Wanderers in the Premier League on Sunday, breaking the record for the longest unbeaten away run in English Football League history in the process.
Liverpool head to United with widest gulf in years
Liverpool moved to 76 points from 32 games with title rivals Manchester City on 74 points from one game fewer, with Pep Guardiola's side hosting Brighton and Hove Albion at the Etihad on Wednesday.
Manchester United's revival came to a disappointing end as Bournemouth forward Joshua King's goal on the stroke of halftime earned a 1-0 victory on a blustery south coast on Saturday.
Images from UEFA Europa League semi-finals played on Thursday.
Cristiano Ronaldo passed the 800-goal mark for club and country, scoring twice as Manchester United beat Arsenal 3-2 in an incident-packed Premier League match on Thursday.
Holders Spain were knocked out of Euro 2016 in a 2-0 defeat by Italy on Monday after goals by Giorgio Chiellini and Graziano Pelle set up a quarter-final with world champions Germany. Chiellini opened the scoring after 33 minutes while Pelle wrapped up the victory in stoppage time to end Spain's reign as European champions which covered the 2008 and 2012 tournaments.
Spain's strong show of unity after the sacking of coach Julen Lopetegui was almost enough to secure victory in their World Cup opener against Portugal on Friday, but Cristiano Ronaldo's late goal took some gloss off a superb performance.
Lewis Hamilton saw his net worth rise by 37 million pounds over the last year.
New Everton boss Sean Dyche's reign began with a shock 1-0 victory over English Premier League leaders Arsenal.
Blaise Matuidi and Zlatan Ibrahimovic scored first half goals as Paris Saint-Germain beat Manchester United 2-0 on Wednesday in their International Champions Cup clash in Chicago.
IMAGES from the Premier League matches played on Sunday.
Manchester United beat AC Milan 5-4 on penalties after their International Champions Cup match in Cardiff's Millennium Stadium ended 2-2 in regulation time on Saturday.
United were unable to create enough quality opportunities to get themselves the goal they needed.
IMAGES from the English Premier League matches played on Saturday
For all their improvement under Klopp, European champions Liverpool have not won at Old Trafford under the German
Images from Saturday's Premier League action.
Images from the English Premier League matches played on Sunday.